The New York Times site today has an interesting graphic that helps one visualize where the money goes in President Obama's proposed budget. You can see it here.
The four biggest boxes are, of course, 1. Health and Human Services (mostly medicare and medicaid), 2. Social Security, 3. Defense, and 4. Treasury (mostly interest on the national debt). We can't do much about (4) except eventually pay down the debt. So clearly any meaningful cuts need to include 1, 2, and 3. But of course neither the Republican proposals nor President Obama's budget proposal touch 1 or 2.